(USAToday) - The third-deadliest fire in California state history has taken lives, homes, businesses and burned some of the nation's most popular vineyards. 

Over 8,000 firefighters are battling the 21 wildfires that have ravaged 191,437 acres. At least 3,500 homes and businesses have been destroyed and an estimated 25,000 people forced to evacuate.

"There are a number of significant wineries that haven't reported in yet, or are still not out of the woods as of this afternoon," said Emily Pennington, managing editor Wine & Spirits Daily. 

Napa and Sonoma counties are home to around 900 wineries (of 4,600 statewide) and represent 13% of the state's output. And the state itself supplies 85% of the nation's wine production, making it the fourth-largest producer of wines after Italy, France and Spain.